Tag: gut health

The administration of denosumab, a high-potency monoclonal antibody used to manage bone complications in cancer patients, has been linked to a rare and life-threatening metabolic crisis characterized by profound mineral depletion. A landmark case study published in JCEM Case Reports details a "hungry bone syndrome-like state" occurring in a 76-year-old male with multiple myeloma, a…

A comprehensive multicenter study published in the Journal of Clinical Endocrinology & Metabolism has uncovered a significant gender-based disparity in the effectiveness of growth-promoting therapies for children with classical congenital adrenal hyperplasia (CAH). The research, which analyzed long-term outcomes for patients with the most common form of the condition, 21-hydroxylase deficiency (21-OHD), suggests that while…

The Endocrine Society has officially released a comprehensive new Clinical Practice Guideline regarding the diagnosis and treatment of central precocious puberty (CPP), signaling a significant shift toward more individualized and conservative management for certain pediatric populations. Presented at ENDO 2026, the Society’s annual meeting, and published in the Journal of Clinical Endocrinology & Metabolism, the…

Redefining the Link Between Sleep and Endocrine Health Obstructive Sleep Apnea Syndrome (OSAS) is a condition characterized by repetitive episodes of partial or complete upper airway obstruction during sleep. These episodes lead to intermittent hypoxia (low oxygen levels), hypercapnia (high carbon dioxide levels), and frequent arousals that fragment sleep architecture. While the cardiovascular and cognitive…

The landscape of metabolic medicine underwent a significant shift during the ENDO 2026 conference in Chicago, Illinois, as the Endocrine Society recognized Dr. Rok Herman with the prestigious 2026 C. Wayne Bardin, MD, International Travel Award. Dr. Herman, an internal medicine resident at the University Medical Centre Ljubljana in Slovenia, received the accolade following the…

Insulet Corporation, a global leader in tubeless insulin pump technology, has announced a landmark partnership with Calm, the world’s leading consumer mental health platform, to address the often-overlooked psychological challenges of living with diabetes. This collaboration marks a significant evolution in the medical technology sector, moving beyond purely physiological management to encompass the emotional and…

Vertex Pharmaceuticals, Inc. and Crinetics Pharmaceuticals, Inc. have announced a definitive agreement under which Vertex will acquire the endocrine-focused biotechnology firm for $85.00 per share in cash. The transaction represents a total equity value of approximately $10.0 billion, or an estimated $8.8 billion net of the cash currently held by Crinetics. This strategic acquisition, which…

Clinical Presentation and the Diagnostic Framework Primary hyperparathyroidism (PHPT) is the third most common endocrine disorder globally, trailing only diabetes mellitus and thyroid diseases. It affects approximately 1% of the adult population, with a significantly higher prevalence among postmenopausal women. The condition is characterized by the overproduction of parathyroid hormone (PTH) from one or more…

The Centers for Medicare & Medicaid Services (CMS) officially released the Calendar Year (CY) 2027 Medicare Physician Fee Schedule (MPFS) proposed rule on July 14, setting the stage for a comprehensive evaluation of how healthcare providers will be reimbursed for services provided to the nation’s senior and disabled populations. The release of the proposed rule…

The American College of Obstetricians and Gynecologists (ACOG), the Society for Women’s Health Research (SWHR), and the Women First Research Coalition (WFRC) officially introduced a landmark policy framework on July 15, designed to address decades of systemic inequities in the American medical landscape. Known as the National Strategy to Close the Women’s Health Gap, the…