The Environmental Protection Agency (EPA) is facing a significant legal challenge following the approval of two new chemical compounds intended for use in the burgeoning datacenter and semiconductor industries, despite internal acknowledgments that the substances pose risks of "sudden death" and other severe health complications. The lawsuit, filed by the nonprofit environmental law organization Earthjustice, alleges that the federal government cleared these chemicals for import and industrial use without sufficient data regarding their lethal thresholds or long-term environmental impacts. The compounds in question belong to a class of chemicals known as photoacid generators, which are increasingly identified as members of the per- and polyfluoroalkyl substances (PFAS) family—often referred to as "forever chemicals" due to their inability to break down in the natural environment.
According to legal filings and documents obtained through the discovery process, the EPA’s own assessment of these substances highlighted a spectrum of extreme physiological risks, including cancer, neurological damage, reproductive harm, and acute eye corrosion. Most alarmingly, the agency’s consent orders reportedly noted that exposure could result in immediate fatality. Despite these findings, and the admission that the agency lacked precise data on the concentrations at which these chemicals become "acutely lethal," the Trump-era EPA moved forward with approvals that allow for the immediate integration of these substances into American industrial supply chains.
The Role of Photoacid Generators in Modern Infrastructure
To understand the gravity of the legal challenge, it is necessary to examine the industrial utility of the chemicals at the center of the dispute. Photoacid generators (PAGs) are specialized compounds used primarily in photolithography, a process essential to the manufacturing of semiconductors and microchips. As the global demand for high-speed computing and data storage grows, datacenters have become the backbone of the modern economy. These facilities require increasingly sophisticated hardware, the production of which often relies on complex chemical processes involving PAGs.
When exposed to light during the chip-making process, PAGs release acids that help etch intricate patterns onto silicon wafers. While their utility in the tech sector is undisputed, their chemical structure often incorporates carbon-fluorine bonds, the hallmark of PFAS. This link has drawn the scrutiny of environmental advocates who argue that the proliferation of these chemicals in datacenters could lead to widespread environmental contamination through wastewater discharge and industrial emissions.
The Earthjustice lawsuit emphasizes that while the tech industry views these chemicals as vital for innovation, the regulatory process governing their introduction was fundamentally flawed. The plaintiff argues that the EPA prioritized industrial expediency over its mandate to protect public health and the environment under the Toxic Substances Control Act (TSCA).
Legal and Regulatory Framework: The TSCA Mandate
The Toxic Substances Control Act is the primary federal law governing the introduction of new chemicals into the U.S. market. Under Section 5 of the TSCA, the EPA is required to review "Premanufacture Notices" (PMNs) for any new chemical substance. The agency must determine whether the substance presents an "unreasonable risk" to human health or the environment. If such a risk is identified, the EPA is legally obligated to implement protections, which can include limiting the volume of production, mandating protective equipment for workers, or outright banning the substance.
In the case of the two datacenter chemicals, the EPA’s consent orders—the legal documents that outline the conditions of approval—explicitly stated that the substances "may present an unreasonable risk." However, rather than prohibiting their use until further safety data could be gathered, the agency allowed for their import and use. Jonathan Kalmuss-Katz, a lead attorney for Earthjustice, contends that this move bypassed the precautionary principles embedded in federal law.
A significant point of contention in the lawsuit is the lack of transparency. Many of the EPA’s documents regarding the chemicals remain heavily redacted, with the agency citing "confidential business information" (CBI) to protect the proprietary interests of the manufacturers. This opacity has made it difficult for independent scientists and the public to evaluate the true extent of the risk or to know exactly which facilities are utilizing these lethal compounds.
Health Implications and the "Sudden Death" Warning
The health risks associated with the two newly approved chemicals are described in the EPA’s own internal documentation as severe and multifaceted. The mention of "sudden death" suggests a level of acute toxicity rarely seen in approved industrial chemicals. This term typically refers to substances that can cause cardiac arrest, respiratory failure, or catastrophic neurological collapse upon even brief exposure.
Beyond the immediate threat of fatality, the chemicals are linked to:
- Carcinogenicity: Potential to trigger cellular mutations leading to various forms of cancer.
- Neurological Damage: Interference with the central nervous system, potentially leading to cognitive impairment or motor dysfunction.
- Reproductive Toxicity: Adverse effects on fertility and fetal development, a common trait among many PFAS compounds.
- Corrosive Effects: Permanent damage to the eyes and skin upon physical contact.
The EPA’s admission that it does not know the exact level at which these chemicals become lethal is a cornerstone of the Earthjustice argument. In traditional toxicology, a "Lethal Dose 50" (LD50) or similar metric is established to understand safety margins. The lawsuit alleges that by approving the chemicals without this data, the EPA has essentially turned industrial workers into "test subjects" for high-risk substances.
Chronology of Approval and Legal Action
The timeline of these approvals reflects a period of significant regulatory shifts within the federal government.
- 2017–2020: The Trump administration implements a series of deregulatory initiatives aimed at streamlining the chemical approval process. The EPA undergoes structural changes that critics argue weakened the influence of career scientists in favor of political appointees.
- Late 2020: The EPA reviews the Premanufacture Notices for the two photoacid generators. Consent orders are drafted, acknowledging the "unreasonable risk" but granting approval for import and use with certain (largely redacted) stipulations.
- 2021–2022: Environmental groups and public health advocates begin flagging inconsistencies in TSCA implementation. Reports emerge of "redacted" safety data regarding PFAS-adjacent chemicals used in the semiconductor industry.
- 2023–2024: Earthjustice, representing a coalition of public health interests, files a formal lawsuit against the EPA. The suit seeks to vacate the approvals and force a more rigorous, transparent review process.
The litigation comes at a time when the Biden administration has pledged to take a harder line on PFAS, yet the specific approvals granted during the previous administration remain in effect, allowing the chemicals to circulate within the U.S. economy.
Industry Context: The Datacenter Boom and PFAS Dependence
The backdrop of this controversy is the unprecedented expansion of the global datacenter market. Driven by the rise of artificial intelligence (AI), cloud computing, and big data, the demand for high-performance microchips has never been higher. This demand places immense pressure on the semiconductor supply chain to source the necessary chemicals for manufacturing.
PFAS have historically been "workhorse" chemicals in this sector due to their unique properties, such as heat resistance and chemical stability. However, as the health risks of PFAS have become better understood, the industry has faced a "PFAS Paradox": the very qualities that make these chemicals industrially useful—their durability and stability—are what make them environmental hazards.
Industry trade groups have frequently argued that a sudden ban on PFAS or related photoacid generators would "cripple" the tech economy and jeopardize national security by stalling domestic chip production. This economic pressure is often cited by analysts as a silent factor in why regulatory agencies might be hesitant to impose strict bans on new chemicals, even when safety data is lacking.
Analysis of Broader Implications
The outcome of this lawsuit could have far-reaching implications for how the United States regulates industrial chemicals. If the court rules in favor of Earthjustice, it could set a precedent that the EPA cannot approve substances when "unreasonable risk" is identified and lethal thresholds are unknown. This would likely force a massive re-evaluation of hundreds of other chemicals approved under similar circumstances.
Furthermore, the case highlights the ongoing battle over "forever chemicals." While the EPA has recently moved to set strict limits on PFAS in drinking water, the regulation of PFAS in industrial manufacturing remains a complex and often inconsistent landscape. The "datacenter chemicals" case serves as a microcosm of the tension between technological advancement and biological safety.
For workers in the semiconductor and datacenter industries, the implications are immediate. The lack of transparency regarding which facilities use these chemicals means that many employees may be unaware of the specific risks they face. Labor advocates argue that without clear labeling and unredacted safety data, the "informed consent" required for workplace safety is impossible to achieve.
Official Responses and Stakeholder Reactions
While the EPA generally does not comment on active litigation, the agency has historically defended its TSCA process as a balance between safety and innovation. In previous statements regarding new chemical reviews, agency representatives have emphasized that consent orders often include requirements for personal protective equipment (PPE) and environmental release limits intended to mitigate the risks identified during the review.
However, Jonathan Kalmuss-Katz of Earthjustice maintains that PPE is a "last line of defense" and should not be used as a justification for approving chemicals with "sudden death" profiles. "The law requires the EPA to ensure that chemicals are safe before they enter our communities and workplaces," Kalmuss-Katz stated. "Approving chemicals that the agency knows are dangerous, while admitting it doesn’t know just how dangerous they are, is a dereliction of duty."
Public health experts have also weighed in, noting that the persistence of PFAS means that any "unreasonable risk" to workers today could become a multi-generational environmental crisis tomorrow. As these chemicals eventually leak from discarded hardware or industrial waste streams, they enter the water cycle, potentially affecting millions of people far removed from the datacenters where the chemicals were originally used.
Conclusion
The legal challenge against the EPA over these two datacenter chemicals marks a critical juncture in environmental law. It pits the rapid growth of the digital infrastructure against the fundamental right to a safe environment and workplace. As the lawsuit moves through the federal court system, it will likely force a public reckoning regarding the "black box" of chemical approvals and the true cost of the hardware that powers the modern world. For now, the chemicals remain in use, their full impact hidden behind redacted documents, even as the warnings of "sudden death" remain on the record.

